Human TSC22D3 activation kit by CRISPRa

CAT#: GA101282

TSC22D3 CRISPRa kit - CRISPR gene activation of human TSC22 domain family member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TSC22D3
• Locus ID: 1831
• Kit Components:

  GA101282G1, TSC22D3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101282G2, TSC22D3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101282G3, TSC22D3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001015881, NM_001318468, NM_001318470, NM_004089, NM_198057
• Synonyms: DIP; DSIPI; GILZ; TSC-22R
• Summary: 'This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]'