Human Torsin A (TOR1A) activation kit by CRISPRa

CAT#: GA101307

TOR1A CRISPRa kit - CRISPR gene activation of human torsin family 1 member A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TOR1A
• Locus ID: 1861
• Kit Components:

  GA101307G1, Torsin A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101307G2, Torsin A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101307G3, Torsin A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000113
• Synonyms: DQ2; DYT1
• Summary: 'The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1. [provided by RefSeq, Jul 2008]'