Human ECE1 activation kit by CRISPRa

CAT#: GA101317

ECE1 CRISPRa kit - CRISPR gene activation of human endothelin converting enzyme 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ECE1
• Locus ID: 1889
• Kit Components:

  GA101317G1, ECE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101317G2, ECE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101317G3, ECE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113347, NM_001113348, NM_001113349, NM_001397
• Synonyms: ECE
• Summary: 'The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]'