Human Thymidine Phosphorylase (TYMP) activation kit by CRISPRa

CAT#: GA101318

TYMP CRISPRa kit - CRISPR gene activation of human thymidine phosphorylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TYMP
• Locus ID: 1890
• Kit Components:

  GA101318G1, Thymidine Phosphorylase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101318G2, Thymidine Phosphorylase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101318G3, Thymidine Phosphorylase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113755, NM_001113756, NM_001257988, NM_001257989, NM_001953
• Synonyms: ECGF; ECGF1; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PDECGF; TP
• Summary: 'This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]'