Human ECHS1 activation kit by CRISPRa

CAT#: GA101320

ECHS1 CRISPRa kit - CRISPR gene activation of human enoyl-CoA hydratase, short chain 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ECHS1
• Locus ID: 1892
• Kit Components:

  GA101320G1, ECHS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101320G2, ECHS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101320G3, ECHS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004092
• Synonyms: SCEH
• Summary: 'The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]'