Human EEF1D activation kit by CRISPRa

CAT#: GA101337

EEF1D CRISPRa kit - CRISPR gene activation of human eukaryotic translation elongation factor 1 delta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EEF1D
• Locus ID: 1936
• Kit Components:

  GA101337G1, EEF1D gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101337G2, EEF1D gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101337G3, EEF1D gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130053, NM_001130054, NM_001130055, NM_001130056, NM_001130057, NM_001195203, NM_001289950, NM_001317743, NM_001330646, NM_001960, NM_032378
• Synonyms: EF-1D; EF1D; FP1047
• Summary: 'This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]'