Human Ephrin A1 (EFNA1) activation kit by CRISPRa

CAT#: GA101341

EFNA1 CRISPRa kit - CRISPR gene activation of human ephrin A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EFNA1
• Locus ID: 1942
• Kit Components:

  GA101341G1, Ephrin A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101341G2, Ephrin A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101341G3, Ephrin A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004428, NM_182685
• Synonyms: B61; ECKLG; EFL1; EPLG1; LERK-1; LERK1; TNFAIP4
• Summary: 'This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]'