Human Ephrin B2 (EFNB2) activation kit by CRISPRa

CAT#: GA101347

EFNB2 CRISPRa kit - CRISPR gene activation of human ephrin B2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EFNB2
• Locus ID: 1948
• Kit Components:

  GA101347G1, Ephrin B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101347G2, Ephrin B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101347G3, Ephrin B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004093
• Synonyms: EPLG5; Htk-L; HTKL; LERK5
• Summary: 'This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]'