Human EGR2 activation kit by CRISPRa

CAT#: GA101357

EGR2 CRISPRa kit - CRISPR gene activation of human early growth response 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EGR2
• Locus ID: 1959
• Kit Components:

  GA101357G1, EGR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101357G2, EGR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101357G3, EGR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000399, NM_001136177, NM_001136178, NM_001136179, NM_001321037
• Synonyms: AT591; CMT1D; CMT4E; KROX20
• Summary: 'The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]'