Human EHHADH activation kit by CRISPRa

CAT#: GA101360

EHHADH CRISPRa kit - CRISPR gene activation of human enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EHHADH
• Locus ID: 1962
• Kit Components:

  GA101360G1, EHHADH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101360G2, EHHADH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101360G3, EHHADH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166415, NM_001966
• Synonyms: ECHD; FRTS3; L-PBE; LBFP; LBP; PBFE
• Summary: 'The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]'