Human CELA1 activation kit by CRISPRa

CAT#: GA101376

CELA1 CRISPRa kit - CRISPR gene activation of human chymotrypsin like elastase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CELA1
• Locus ID: 1990
• Kit Components:

  GA101376G1, CELA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101376G2, CELA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101376G3, CELA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001971
• Synonyms: ELA1
• Summary: 'Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]'