Human ELK3 activation kit by CRISPRa

CAT#: GA101389

ELK3 CRISPRa kit - CRISPR gene activation of human ETS transcription factor ELK3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELK3
• Locus ID: 2004
• Kit Components:

  GA101389G1, ELK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101389G2, ELK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101389G3, ELK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303511, NM_005230
• Synonyms: ERP; NET; SAP-2; SAP2
• Summary: 'This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]'