Human Eph receptor A3 (EPHA3) activation kit by CRISPRa

CAT#: GA101421

EPHA3 CRISPRa kit - CRISPR gene activation of human EPH receptor A3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EPHA3
• Locus ID: 2042
• Kit Components:

  GA101421G1, Eph receptor A3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101421G2, Eph receptor A3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101421G3, Eph receptor A3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005233, NM_182644
• Synonyms: EK4; ETK; ETK1; HEK; HEK4; TYRO4
• Summary: 'This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]'