Human Epoxide hydrolase (EPHX1) activation kit by CRISPRa

CAT#: GA101431

EPHX1 CRISPRa kit - CRISPR gene activation of human epoxide hydrolase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EPHX1
• Locus ID: 2052
• Kit Components:

  GA101431G1, Epoxide hydrolase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101431G2, Epoxide hydrolase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101431G3, Epoxide hydrolase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000120, NM_001136018, NM_001291163
• Synonyms: EPHX; EPOX; HYL1; MEH
• Summary: 'Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008]'