Human EREG activation kit by CRISPRa

CAT#: GA101446

EREG CRISPRa kit - CRISPR gene activation of human epiregulin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EREG
• Locus ID: 2069
• Kit Components:

  GA101446G1, EREG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101446G2, EREG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101446G3, EREG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001432
• Synonyms: Ep; EPR; ER
• Summary: 'This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015]'