Human Estrogen Related Receptor alpha (ESRRA) activation kit by CRISPRa

CAT#: GA101463

ESRRA CRISPRa kit - CRISPR gene activation of human estrogen related receptor alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ESRRA
• Locus ID: 2101
• Kit Components:

  GA101463G1, Estrogen Related Receptor alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101463G2, Estrogen Related Receptor alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101463G3, Estrogen Related Receptor alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282450, NM_001282451, NM_004451
• Synonyms: ERR1; ERRa; ERRalpha; ESRL1; NR3B1
• Summary: 'The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq, Jun 2019]'