Human ETFDH activation kit by CRISPRa

CAT#: GA101469

ETFDH CRISPRa kit - CRISPR gene activation of human electron transfer flavoprotein dehydrogenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ETFDH
• Locus ID: 2110
• Kit Components:

  GA101469G1, ETFDH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101469G2, ETFDH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101469G3, ETFDH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281737, NM_001281738, NM_004453
• Synonyms: ETFQO; MADD
• Summary: 'This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed. [provided by RefSeq, Aug 2013]'