Human EXT2 activation kit by CRISPRa

CAT#: GA101486

EXT2 CRISPRa kit - CRISPR gene activation of human exostosin glycosyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXT2
• Locus ID: 2132
• Kit Components:

  GA101486G1, EXT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101486G2, EXT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101486G3, EXT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000401, NM_001178083, NM_207122
• Synonyms: SOTV
• Summary: 'This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]'