Human EXTL3 activation kit by CRISPRa

CAT#: GA101489

EXTL3 CRISPRa kit - CRISPR gene activation of human exostosin like glycosyltransferase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXTL3
• Locus ID: 2137
• Kit Components:

  GA101489G1, EXTL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101489G2, EXTL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101489G3, EXTL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001440, NR_073468, NR_073469
• Synonyms: BOTV; EXTL1L; EXTR1; REGR; RPR
• Summary: 'This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]'