Human EZH1 activation kit by CRISPRa

CAT#: GA101493

EZH1 CRISPRa kit - CRISPR gene activation of human enhancer of zeste 1 polycomb repressive complex 2 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EZH1
• Locus ID: 2145
• Kit Components:

  GA101493G1, EZH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101493G2, EZH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101493G3, EZH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001991, NM_001321079, NM_001321081, NM_001321082
• Synonyms: KMT6B
• Summary: 'EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009]'