Human Thrombin Receptor (F2R) activation kit by CRISPRa

CAT#: GA101496

F2R CRISPRa kit - CRISPR gene activation of human coagulation factor II thrombin receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: F2R
• Locus ID: 2149
• Kit Components:

  GA101496G1, Thrombin Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101496G2, Thrombin Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101496G3, Thrombin Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001311313, NM_001992, N35000
• Synonyms: CF2R; HTR; PAR-1; PAR1; TR
• Summary: 'Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]'