Human Proteinase Activated Receptor 3 (F2RL2) activation kit by CRISPRa

CAT#: GA101498

F2RL2 CRISPRa kit - CRISPR gene activation of human coagulation factor II thrombin receptor like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: F2RL2
• Locus ID: 2151
• Kit Components:

  GA101498G1, Proteinase Activated Receptor 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101498G2, Proteinase Activated Receptor 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101498G3, Proteinase Activated Receptor 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256566, NM_004101
• Synonyms: PAR-3; PAR3
• Summary: 'This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]'