Human FABP3 activation kit by CRISPRa

CAT#: GA101513

FABP3 CRISPRa kit - CRISPR gene activation of human fatty acid binding protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FABP3
• Locus ID: 2170
• Kit Components:

  GA101513G1, FABP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101513G2, FABP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101513G3, FABP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004102, NM_001320996
• Synonyms: FABP11; H-FABP; M-FABP; MDGI; O-FABP
• Summary: 'The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]'