Human ACSL1 activation kit by CRISPRa

CAT#: GA101521

ACSL1 CRISPRa kit - CRISPR gene activation of human acyl-CoA synthetase long chain family member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACSL1
• Locus ID: 2180
• Kit Components:

  GA101521G1, ACSL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101521G2, ACSL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101521G3, ACSL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286708, NM_001286710, NM_001286711, NM_001286712, NM_001995, NM_021122
• Synonyms: ACS1; FACL1; FACL2; LACS; LACS1; LACS2
• Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]