Human Fatty Acid Synthase (FASN) activation kit by CRISPRa

CAT#: GA101533

FASN CRISPRa kit - CRISPR gene activation of human fatty acid synthase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FASN
• Locus ID: 2194
• Kit Components:

  GA101533G1, Fatty Acid Synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101533G2, Fatty Acid Synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101533G3, Fatty Acid Synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004104
• Synonyms: FAS; OA-519; SDR27X1
• Summary: 'The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]'