Human CD23 (FCER2) activation kit by CRISPRa

CAT#: GA101546

FCER2 CRISPRa kit - CRISPR gene activation of human Fc fragment of IgE receptor II

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCER2
• Locus ID: 2208
• Kit Components:

  GA101546G1, CD23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101546G2, CD23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101546G3, CD23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001207019, NM_001220500, NM_002002
• Synonyms: BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF
• Summary: 'The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]'