Human CD64 (FCGR1B) activation kit by CRISPRa

CAT#: GA101548

FCGR1B CRISPRa kit - CRISPR gene activation of human Fc fragment of IgG receptor Ib

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCGR1B
• Locus ID: 2210
• Kit Components:

  GA101548G1, CD64 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101548G2, CD64 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101548G3, CD64 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001004340, NM_001017986, NM_001244910, NR_045213
• Synonyms: CD64b; IGFRB
• Summary: 'Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene likely encodes a non-functional protein that is not detectable at the cell surface and binds ligand with low affinity. [provided by RefSeq, Nov 2019]'