Human CD32A (FCGR2A) activation kit by CRISPRa

CAT#: GA101549

FCGR2A CRISPRa kit - CRISPR gene activation of human Fc fragment of IgG receptor IIa

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCGR2A
• Locus ID: 2212
• Kit Components:

  GA101549G1, CD32A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101549G2, CD32A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101549G3, CD32A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136219, NM_021642
• Synonyms: CD32; CD32A; CDw32; FCG2; FcGR; FCGR2; FCGR2A1; IGFR2
• Summary: 'This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]'