Human CD32B (FCGR2B) activation kit by CRISPRa

CAT#: GA101550

FCGR2B CRISPRa kit - CRISPR gene activation of human Fc fragment of IgG receptor IIb

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCGR2B
• Locus ID: 2213
• Kit Components:

  GA101550G1, CD32B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101550G2, CD32B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101550G3, CD32B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002273, NM_001002274, NM_001002275, NM_001190828, NM_004001
• Synonyms: CD32; CD32B; FCG2; FCGR2; IGFR2
• Summary: 'The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]'