Human Glypican 4 (GPC4) activation kit by CRISPRa

CAT#: GA101563

GPC4 CRISPRa kit - CRISPR gene activation of human glypican 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPC4
• Locus ID: 2239
• Kit Components:

  GA101563G1, Glypican 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101563G2, Glypican 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101563G3, Glypican 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001448
• Synonyms: K-glypican
• Summary: 'Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]'