Human FGF4 activation kit by CRISPRa

CAT#: GA101572

FGF4 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FGF4
• Locus ID: 2249
• Kit Components:

  GA101572G1, FGF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101572G2, FGF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101572G3, FGF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002007
• Synonyms: HBGF-4; HST; HST-1; HSTF1; K-FGF; KFGF
• Summary: 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]'