Human FGF13 activation kit by CRISPRa

CAT#: GA101581

FGF13 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FGF13
• Locus ID: 2258
• Kit Components:

  GA101581G1, FGF13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101581G2, FGF13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101581G3, FGF13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001139498, NM_001139500, NM_001139501, NM_001139502, NM_004114, NM_033642
• Synonyms: FGF-13; FGF2; FHF-2; FHF2
• Summary: 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked cognitive disability mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]'