Human FKBP1B activation kit by CRISPRa

CAT#: GA101598

FKBP1B CRISPRa kit - CRISPR gene activation of human FKBP prolyl isomerase 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FKBP1B
• Locus ID: 2281
• Kit Components:

  GA101598G1, FKBP1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101598G2, FKBP1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101598G3, FKBP1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001322963, NM_001322964, NM_004116, NM_054033, NR_136536, NR_136538, NR_136539
• Synonyms: FKBP1L; FKBP12.6; OTK4; PKBP1L; PPIase
• Summary: 'The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]'