Human FOXC1 activation kit by CRISPRa

CAT#: GA101606

FOXC1 CRISPRa kit - CRISPR gene activation of human forkhead box C1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXC1
• Locus ID: 2296
• Kit Components:

  GA101606G1, FOXC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101606G2, FOXC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101606G3, FOXC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001453
• Synonyms: ARA; FKHL7; FREAC-3; FREAC3; IGDA; IHG1; IRID1; RIEG3
• Summary: 'This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008]'