Human FOXO1 activation kit by CRISPRa

CAT#: GA101618

FOXO1 CRISPRa kit - CRISPR gene activation of human forkhead box O1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXO1
• Locus ID: 2308
• Kit Components:

  GA101618G1, FOXO1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101618G2, FOXO1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101618G3, FOXO1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002015
• Synonyms: FKH1; FKHR; FOXO1A
• Summary: 'This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]'