Human FOLR3 activation kit by CRISPRa

CAT#: GA101647

FOLR3 CRISPRa kit - CRISPR gene activation of human folate receptor gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOLR3
• Locus ID: 2352
• Kit Components:

  GA101647G1, FOLR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101647G2, FOLR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101647G3, FOLR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000804, NM_001318045
• Synonyms: FR-G; FR-gamma; gamma-hFR
• Summary: 'This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]'