Human Ferritin Light Chain (FTL) activation kit by CRISPRa

CAT#: GA101665

FTL CRISPRa kit - CRISPR gene activation of human ferritin light chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FTL
• Locus ID: 2512
• Kit Components:

  GA101665G1, Ferritin Light Chain gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101665G2, Ferritin Light Chain gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101665G3, Ferritin Light Chain gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000146
• Synonyms: LFTD; NBIA3
• Summary: 'This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]'