Human DARC (ACKR1) activation kit by CRISPRa

CAT#: GA101681

ACKR1 CRISPRa kit - CRISPR gene activation of human atypical chemokine receptor 1 (Duffy blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACKR1
• Locus ID: 2532
• Kit Components:

  GA101681G1, DARC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101681G2, DARC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101681G3, DARC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001122951, NM_002036
• Synonyms: CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1
• Summary: 'The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'