Human GABPB2 (GABPB1) activation kit by CRISPRa

CAT#: GA101696

GABPB1 CRISPRa kit - CRISPR gene activation of human GA binding protein transcription factor subunit beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GABPB1
• Locus ID: 2553
• Kit Components:

  GA101696G1, GABPB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101696G2, GABPB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101696G3, GABPB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320910, NM_001320915, NM_002041, NM_005254, NM_016654, NM_016655, NM_181427
• Synonyms: BABPB2; E4TF1; E4TF1-47; E4TF1-53; E4TF1B; GABPB; GABPB-1; GABPB2; NRF2B1; NRF2B2
• Summary: 'This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'