Human GABRP activation kit by CRISPRa

CAT#: GA101711

GABRP CRISPRa kit - CRISPR gene activation of human gamma-aminobutyric acid type A receptor pi subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GABRP
• Locus ID: 2568
• Kit Components:

  GA101711G1, GABRP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101711G2, GABRP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101711G3, GABRP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291985, NM_014211
• Summary: 'The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]'