Human GALNS activation kit by CRISPRa

CAT#: GA101728

GALNS CRISPRa kit - CRISPR gene activation of human galactosamine (N-acetyl)-6-sulfatase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GALNS
• Locus ID: 2588
• Kit Components:

  GA101728G1, GALNS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101728G2, GALNS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101728G3, GALNS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000512, NM_001323543, NM_001323544
• Synonyms: GalN6S; GALNAC6S; GAS; MPS4A
• Summary: 'This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008]'