Human GAS 6 (GAS6) activation kit by CRISPRa

CAT#: GA101742

GAS6 CRISPRa kit - CRISPR gene activation of human growth arrest specific 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GAS6
• Locus ID: 2621
• Kit Components:

  GA101742G1, GAS 6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101742G2, GAS 6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101742G3, GAS 6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000820, NM_001143945, NM_001143946
• Synonyms: AXLLG; AXSF
• Summary: 'This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014]'