Human GDI2 activation kit by CRISPRa

CAT#: GA101779

GDI2 CRISPRa kit - CRISPR gene activation of human GDP dissociation inhibitor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GDI2
• Locus ID: 2665
• Kit Components:

  GA101779G1, GDI2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101779G2, GDI2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101779G3, GDI2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001115156, NM_001494
• Synonyms: HEL-S-46e; RABGDIB
• Summary: 'GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]'