Human GGT1 activation kit by CRISPRa

CAT#: GA101790

GGT1 CRISPRa kit - CRISPR gene activation of human gamma-glutamyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GGT1
• Locus ID: 2678
• Kit Components:

  GA101790G1, GGT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101790G2, GGT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101790G3, GGT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032364, NM_001032365, NM_001288833, NM_005265, NM_013421, NM_013430
• Synonyms: CD224; D22S672; D22S732; GGT; GGT 1; GTG
• Summary: 'The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]'