Human GGT7 activation kit by CRISPRa

CAT#: GA101792

GGT7 CRISPRa kit - CRISPR gene activation of human gamma-glutamyltransferase 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GGT7
• Locus ID: 2686
• Kit Components:

  GA101792G1, GGT7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101792G2, GGT7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101792G3, GGT7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_052830, NM_178025, NM_178026, NM_001351702
• Synonyms: GGTL5, D20S101, dJ18C9.2
• Summary: 'This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008]'