Human GIP activation kit by CRISPRa

CAT#: GA101801

GIP CRISPRa kit - CRISPR gene activation of human gastric inhibitory polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GIP
• Locus ID: 2695
• Kit Components:

  GA101801G1, GIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101801G2, GIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101801G3, GIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004123
• Synonyms: gastric inhibitory polypeptide; glucose-dependent insulinotropic polypeptide
• Summary: 'This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]'