Human GJA8 activation kit by CRISPRa

CAT#: GA101807

GJA8 CRISPRa kit - CRISPR gene activation of human gap junction protein alpha 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GJA8
• Locus ID: 2703
• Kit Components:

  GA101807G1, GJA8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101807G2, GJA8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101807G3, GJA8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005267
• Synonyms: CAE; CAE1; CTRCT1; CX50; CZP1; MP70
• Summary: 'This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009]'