Human GLB1 activation kit by CRISPRa

CAT#: GA101816

GLB1 CRISPRa kit - CRISPR gene activation of human galactosidase beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLB1
• Locus ID: 2720
• Kit Components:

  GA101816G1, GLB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101816G2, GLB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101816G3, GLB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000404, NM_001079811, NM_001135602, NM_001317040
• Synonyms: EBP; ELNR1; MPS4B
• Summary: 'This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. [provided by RefSeq, Nov 2015]'