Human GLUD2 activation kit by CRISPRa

CAT#: GA101834

GLUD2 CRISPRa kit - CRISPR gene activation of human glutamate dehydrogenase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLUD2
• Locus ID: 2747
• Kit Components:

  GA101834G1, GLUD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101834G2, GLUD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101834G3, GLUD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012084
• Synonyms: GDH2; GLUDP1
• Summary: 'The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010]'