Human G protein alpha inhibitor 1 (GNAI1) activation kit by CRISPRa

CAT#: GA101844

GNAI1 CRISPRa kit - CRISPR gene activation of human G protein subunit alpha i1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GNAI1
• Locus ID: 2770
• Kit Components:

  GA101844G1, GNAI1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101844G2, GNAI1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101844G3, GNAI1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256414, NM_002069
• Synonyms: Gi
• Summary: Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]